Transcutaneous spinal cord stimulation improves postural stability in individuals with multiple sclerosis

BackgroundWidespread demyelination in the central nervous system can lead to progressive sensorimotor impairments following multiple sclerosis, with compromised postural stability during standing being a common consequence. As such, clinical strategies are needed improve sclerosis. The objective of this study was therefore investigate effect non-invasive transcutaneous spinal stimulation on upright individuals sclerosis.MethodsCenter pressure displacement and electromyograms from soleus tibialis anterior were recorded seven sclerosis without stimulation. Center muscle activity measures calculated compared between no conditions. relationship center quantified using cross-correlation analysis.ResultsFor stimulation, significantly improved eyes closed: time- frequency-domain obtained anterior-posterior fluctuation decreased increased, respectively, lower Conversely, differences found when open.ConclusionFollowing closed, presumably by catalyzing proprioceptive function. Future work should confirm underlying mechanisms explore value for